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Worlds Strongest Man Mitchell Hooper and Ebenezer Samuel, CSCS break it down on #strongtalk

It acts directly on the hypothalamus to stimulate the release of gonadotropin-releasing hormone (GnRH), which in turn triggers the pituitary gland to secrete LH and FSH

The non-enzymatic mitochondrial protein hyperacetylation induced by the increased availability of mitochondrial acetyl-CoA avoids the risk associated with mitochondria overfeeding, restraining the activity of the respiratory complex I and modulating CACT activity

DOI: 10.1172/JCI5461

Larger and longer-term clinical trials are needed, and supplementation with other compounds important for methionine metabolism, such as vitamin B6, should be considered in ALD patients

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