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Omega-3 FAs also possess antithrombotic properties, help maintain tissue microperfusion, and stimulate the production of prostaglandin E2

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found that Receptor-interacting protein 2 (RIP2) can regulate cartilage degradation and oxidative stress in IL-1 -treated chondrocytes by regulating TRAF3 expression and p38-MAPK pathway activation (Pan et al., 2021)