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Since DFO is membrane impermeable and accumulates in lysosomes 18 , we believe that it protects the cells against ferroptosis by chelating lysosomal iron as described previously 47

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Such binding may displace other regulatory proteins, making DNA more accessible for transcriptional machinery, potentially inducing neuronal cell differentiation in retinal and periodontal ligament stem cells (hPDLSCs)

Discussion In this study, we demonstrated that AD-related A pathology is associated with changes in protein expression of ferroptosis-related proteins in the human brain

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