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Although PHHs remain the gold standard for in vitro liver models, their availability, variability, and rapid dedifferentiation underscore the values of iHLOs as a scalable, reproducible alternative

This makes them popular with clients chasing anti-aging and performance goals

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Dihexa is not currently regulated or banned by major doping agencies like WADA, but its novel mechanism and unapproved status underscore the need for careful clinical evaluation before widespread use

In addition, the vector carrying the jr PPO1-wt gene was used as a template for the mutagenesis experiments

We appreciate your ongoing support as we adapt to these regulatory adjustments