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In rat studies, DSIP administration decreased plasma corticosterone (the rodent equivalent of cortisol) by approximately 30%

10.1016/j.tibs.2015.12.004 Trends Biochem

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Understanding what the research actually shows versus marketing claims is essential before considering this intervention

In sharp contrast, someone whose deficiency is purely diet-related might just need a short series of shots to replenish their stores before they can switch to high-dose oral supplements