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185 GM-CSF derived from breast cancer tumor cells can promote ARG1 expression in tumor-infiltrating myeloid cells through STAT3 and p38 MAPK signaling pathways, enhance the function of tumor-infiltrating myeloid cells, and promote the development of immunosuppressive TME (Fig

Materials and methods Institutional Review Board approval was obtained at the University of Washington for this single-center study of 15 participants with mid-stage PD