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Erastin can directly inhibit cystine uptake, leading to ferroptosis, whereas RSL3 can inhibit GPX4 to induce ferroptosis ( Figure 1 ) (58)

Incorporating omega-3 rich foods or high-quality supplements early in recovery may offer supportive benefits, particularly for athletes and students seeking a quicker return to academic and physical activity

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Nrf2 activation promotes GSH-mediated antioxidant defense.Bottom right (Parkinsons disease): dopaminergic neurons in the substantia nigra accumulate Lewy bodies and undergo degeneration

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