GSH shortages are related to the overall aging process, exacerbating weakness and frailty as we mature
Studies have shown that B12 injections can lead to improvement in behavioral and cognitive functions
Chronic high-dose use may not be wise for someone with cardiovascular disease risk, high LDL cholesterol, kidney disease, or a medical history that already warrants monitoring
Using this method, we can safely deliver larger doses that would otherwise not be fully absorbed from oral supplements
However, the study was small, lacked a placebo control and evaluated biomarkers rather than long-term clinical outcomes
In a rat model of cyclophosphamide-induced POI, salidroside (2550 mgkgday) significantly ameliorated ovarian damage by restoring follicular morphology, elevating serum estradiol and AMH levels, and reducing FSH concentrations