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This difference can influence nicotine release: the finely ground tobacco in snus releases nicotine readily under the lip, whereas the coarser tobacco in chew bags might release nicotine a bit more slowly unless its chewed to help break it up

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But Pip and his pals weren't just cynical bandwagon-hitching opportunists: Virginia Slims would also play a small but significant part in a genuine advance

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Three clinical forms are noted(1) keratotic/reticular, (2) erythematous/erosive, and (3) ulcerativeand these often occur in combination.21,54 The most recognizable is the keratotic/reticular form (Wickham striae) that is usually not painful