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Nitric oxide as a regulator in preimplantation embryo development and apoptosis

The interaction was also disrupted by tumor-associated mutations in the -domain of pVHL and loss of interaction was associated with defective HIF-1 ubiquitination and regulation, defining a mechanism by which these mutations generate a constitutively hypoxic pattern of gene expression promoting angiogenesis [8487]

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Endothelial cells may mediate early inflammatory responses through expression of proinflammatory factors, like IL-1 (Iannucci et al., 2022), that activate microglia

ACSL4 facilitates long-chain unsaturated fatty acid (e.g., arachidonic acid 20:4, adrenoic acid 22:4) incorporation into phospholipids through coordinated action with lysophospholipid acyltransferases

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