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For pernicious anaemia, maintenance injections are typically given every 2-3 months lifelong

Hydroxocobalamin is longer-acting and stays in your system longer, making it ideal for more sustained energy between appointments

J Popul Ther Clin Pharmacol

In the UK, B12 replacement is typically administered via intramuscular hydroxocobalamin injections for patients with confirmed deficiency, particularly those with malabsorption or pernicious anaemia, as specified in the BNF and NICE CKS guidance on B12 and folate deficiency anaemia

Myth: Massaging the area helps the B12 spread and work faster Reality: Massaging may spread the fluid and increase bruising or soreness without improving how the vitamin works

For example, individuals with NAFLD exhibit increased intestinal permeability and prevalence of small intestine bacterial overgrowth, and these factors are associated with the severity of hepatic steatosis 19