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The mechanism of action isnt well understood, but its believed it doesnt affect the tendon tissue cells directly, but rather that either works by activating other repair cells that can help tendons or ligaments or making the human growth factor receptor on the repair cells more sensitive (3)

doi: 10.1038/d41586-022-00382-2 102 MontoyaJGKogelnikAMBhangooMLunnMRFlamandLMerrihewLEet al

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Other Common Reasons for Pain After PRP Injections While post-PRP pain is often a normal part of the healing process, there are several other reasons why a patient might experience discomfort after treatment