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Generally, the dysregulation of apoptosis of citrullinated proteins leads to increased accessibility of intracellular antigens to the immune system, resulting in the production of autoantibodies, immune complex formation, upregulation of pro-inflammatory cytokines, and ultimately leading to chronic inflammation in RA [11]

Gradual dose escalation helps identify whether the peptide retains expected activity

Mereness, J

However, no formal drug interaction studies have been conducted

Its ability to enhance healing processes without the need for additional carriers simplifies treatment protocols and makes it a more convenient option for patients and healthcare providers alike

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