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The peptide has high affinity for copper(II) the binding constant is approximately 10^16 M^-1

Discussion 1) The results of this study completed by McCoy et al systematically evaluated the metabolic stability, BBB permeability, procognitive activity, and synaptogenic potential of Dihexa and other Nle-AngIV analogs, ultimately aiming to identify a therapeutic agent for dementia

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Enhances bone healing: Accelerated bone formation and improved graft healing in rat anterior cruciate ligament reconstruction model 2