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For FY 2023 and subsequent years, our policy is to include the wage data of hospitals that have reclassified from urban to rural under section 1886(d)(8)(E) of the Act (as implemented in the regulations at 412.103) and have no MGCRB ( reclassification in the calculation of the rural floor, and to include the wage data of such hospitals in the calculation of the wage index for rural areas in the State in which the county is located as referred to in section 1886(d)(8)(C)(iii) of the Act

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However, absence of extensive research on newer variants does not mean they are ineffective, just less studied

Matsuzaki et al., 2001

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