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For comparison, sulfasalazine (50 mg/kg intraperitoneally, once daily) (moderately effective) or 6--methylprednisolone (1.0 mg/kg intraperitoneally, once daily) (aggravation) was given

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2023 (Source: Barrons.com)

Graf and Kastin documented that DSIP affects not just sleep itself but the neuroendocrine systems that govern sleep including ACTH, growth hormone release patterns, and circadian oscillators (Graf & Kastin, 1984)