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Early pharmacologic strategies primarily targeted isolated components of metabolic dysregulation, such as enhancing insulin secretion, reducing hepatic glucose output, slowing intestinal glucose absorption, or suppressing appetite
2004 Sep 1;58(2):35768
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Tesamorelin and Metabolic Syndrome: A Direct Relationship Metabolic syndrome is defined by a cluster of five risk factors: elevated waist circumference, high triglycerides, low HDL cholesterol, elevated blood pressure, and impaired fasting glucose
ROS generation was detected using a Leica fluorescence microscope (Leica DM6000B) and Leica LAS X software, and the quantitative analysis was performed with ImageJ
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