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Impurities can act as confounding variables, producing false-positive or false-negative results

Differential effects of ATP7A and ATP7B regulating copper metabolism MURR1 domain protein 1 (COMMD1) on the formation of mutant Cu, Zn-SOD1 fibrils (increase) or parkin inclusions (decrease) as well as the Htt aggregates (unaltered), however, suggest mechanistic diversity [286]

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This issue underscores the necessity for alternative drug delivery methods, leading to the emergence of Exos as a promising therapeutic option for neurodegenerative diseases [113]

73 Fiber has also been shown to reduce other independent risk factors for gout, including hypertension74,75 and high cholesterol