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This redefinition of OA from a purely mechanical to a metabolic-inflammatory disorder opens transformative avenues for management, positioning nutritional intervention not merely as supportive care, but as a cornerstone of disease-modifying strategy

Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2

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2-adrenergic receptor signaling regulates metabolic pathways critical to myeloid-derived suppressor cell function within the TME

doi: 10.1016/j.redox.2015.07.012