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Pregnancy and breastfeeding represent contraindications

A 2013 meta-analysis of 53 placebo-controlled trials evaluated the effect of vitamin C supplementation on the incidence, duration, or severity of the common cold when taken as a continuous daily supplement (43 trials) or as therapy upon onset of cold symptoms (10 trials) (212)

NNMT enzyme inhibition biochemical studies have characterised 5-Amino-1MQ as a potent, selective NNMT inhibitor in cell-free and cell-culture assays

GLOW has no trial-established dose that combines the three compounds

Beyond adipose metabolism, 5-Amino-1MQ contributes to increased intracellular NAD+ availability , improving mitochondrial respiration and ATP synthesis

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