A randomized controlled trial of topical GHK-Cu cream for facial rejuvenation in postmenopausal women
It is a substrate for -ketoglutarate dehydrogenase (OGDH) in oxidative reactions generating succinyl-CoA and isocitrate dehydrogenase 1 (IDH1) or isocitrate dehydrogenase 2 (IDH2), which catalyze the reductive carboxylation reaction converting -KG to isocitrate
[PubMed: 3443807] 82
127 Further, mice homozygous for the Plin1 deletion exhibit high basal lipolysis and are unresponsive to adrenergic stimulation, confirming that PLIN is actively controls lipolysis 128,129 Taken together, all the evidence supports that white adipose tissue (WAT) lipolysis suppression of insulin also associated with hepatic gluconeogenes, and the mechanisms of IR include complex mediators and metabolic networks
That means that the molecules are designed to combine with body fluids and absorb through the mucous membranes of the body (mouth and digestive tract), instead of relying on absorption through the gut (which is no good)
GHK-Cu (Copper Tripeptide-1) and AHK-Cu are two potent peptides known for their remarkable ability to stimulate hair follicles and support hair regrowth
