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PINK1 was found to interact with an alternative ubiquitin E3 ligase component, F-box only protein 15 (Fbxo15), which promoted mitochondrial instability in this model ( XENOPHAGY Autophagy can contribute to the immune response by providing a mechanism for the selective intracellular degradation of invading pathogens, a process termed xenophagy. Invading bacteria are tagged for removal with ubiquitin

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