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The company was founded by Dr

Bisht, S

Ethics declarations Conflict of interest The authors declared that they have no conflict of interest in this work

Screening for Functional TMABA Dehydrogenases An in vitro photometric enzyme assay based on cell extracts was chosen for screening TMABA dehydrogenase activity, as it is easily feasible due to the co-conversion of NAD + to NADH in the TMABADH reaction (Figure 3)

The core direction of future research should focus on directly verifying the causal relationship between local joint ferroptosis and gut microbiota dysbiosis through germ-free OA mouse models, fecal microbiota transplantation experiments, or conditional knockout models of key genes for chondrocyte-specific ferroptosis (such as GPX4 and ACSL4)

JAMA 302 , 14441450 (2009)