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In 2019, liver-expressed antimicrobial peptide (LEAP2), initially discovered as an antimicrobial peptide produced in the liver, was identified to be upregulated in the stomach of diet-induced obese mice after vertical sleeve gastrectomy

Thus, changes in the metabolites involved in the synthesis of sulfur-containing amino acids, which are associated with a cellular redox state, were observed

Nakayama et al., 2020)

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