Neomycin, colchicine, para-aminosalicylic acid, or excessive alcohol intake longer than two weeks may cause malabsorption of vitamin B12. Chloramphenicol and other drugs having bone marrow suppressant properties may cause a lack of therapeutic response to vitamin B12
Other lipotropic injection side effects include: Headaches and light headedness Stomach upsets such as mild nausea and mild diarrhea Allergic reactions (itching, hives, shortness of breath, wheezing, swelling of the tongue, throat, or mouth) although rare, can also occur
Testing before supplementing is key
According to NICE guidance, hydroxocobalamin injections are the recommended first-line treatment for pernicious anaemia and other malabsorption-related deficiencies
One would surely argue that some groups are more at risk for B12 deficiencies and could, therefore, benefit from injections: vegetarians and vegans have impaired B12 absorption due to changes from diet, while older adults have changes due to aging
Liposomal delivery systems encapsulate AHK-Cu in lipid spheres, potentially improving penetration through the stratum corneum and protecting the peptide from degradation