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For regular drinkers (3+ drinks per week), daily NAC (600mg) or alpha-lipoic acid (300mg) supports baseline glutathione synthesis without suppressing endogenous production, and both have been studied in chronic alcohol use populations with positive hepatoprotective outcomes

methodology, F.P

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[DOI] [PMC free article] [PubMed] [Google Scholar] 135.Tan J., McKenzie C., Potamitis M., Thorburn A., Mackay C., Macia L

The peptide's half-life is approximately 46 hours, so timed administration ensures peak plasma concentration coincides with peak receptor expression

Antioxidant Regeneration Glutathione is called the "master antioxidant" for a reason