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Changes in the cellular redox state can alter the oxidation state of metabolic enzymes, resulting in changes in their activity and altered flux through upstream and downstream pathways

Hemodynamic agents including milrinone and dobutamine are also under exploration for carefully selected patients, given their ability to enhance cerebral perfusion, although safety concerns necessitate rigorous patient stratification 36

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(21) It is highly stable, remaining intact in gastric juice for over 24 hours, and has a strong safety profile (no lethal dose identified)

Suraokar MB, Nunez MI, Diao L, Chow CW, Kim D, Behrens C, Lin H, Lee S, Raso G, Moran C, Rice D, Mehran R, Lee JJ, Pass HI, Wang J, Momin AA, James BP, Corvalan A, Coombes K, Tsao A, Wistuba II