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Hierarchical clustering of commonly engaged proteins by the fold increase in target engagement in senescent versus non-senescent conditions (referred to as senescence selectivity) identified broadly highly-reactive proteins, clusters of proteins with specificity to certain chemotypes and others (such as GPX4) that were enriched in probes related to three different SCLAs (Fig

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10.1111/j.1365-313X.2008.03477.x 41 GrzamA.TennstedtP.ClemensS.HellR.MeyerA

2 microdeletion gene Mrpl40 disrupts short-term synaptic plasticity and working memory through dysregulation of mitochondrial calcium

Further research investigating time-course changes in citrulline concentration following CM supplementation is required to determine the optimal strategy, although the best recommendation at the moment would be 1 h prior to exercise

The degree of early oxidative stress presaged the behavioral scores across all withdrawing neonatal rat groups