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FOXO4-DRI Potential Selectivity As mentioned, FOXO4-DRI is believed to selectively disrupt the binding of FOXO4 to p53, which may lead to the activation of p53, which in turn may stimulate the process of removing senescent cells

Alphafold3 36 predictions support a very similar OCTN1 sodium-binding site to OCTN2 (Supplementary Fig

Reverse transcription to cDNA was carried out with All-in-One First-Strand cDNA Synthesis Kit (GeneCopoeia, USA) with oligo-dT primer in a final volume of 25 l at 42C for 1 h

Apply in the evening to clean, dry skin