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Researchers expect preclinical research to advance before testing these peptides in humans

doi:10.3390/biomedicines11010240

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Exogenous testosterone also exerts negative feedback on the hypothalamic-pituitary-gonadal axis: it suppresses pituitary release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to reduced endogenous testosterone production and diminished spermatogenesis