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Conflicts of Interest The authors declare no conflict of interest References 1.Holshue M., DeBolt C., Lindquist S., Lofy K., Wiesman J., Bruce H., Spitters C., Ericson K., Wilkerson S., Tural A., et al

The observed increase in blood hemoglobin is likely a direct result of the extracts rich mineral content and its positive effect on intestinal integrity and permeability 44

Int J Clin Pract 72(6):e13208

Sirtuin 1 (SIRT1) negatively regulates GH-induced IGF-1 production in the liver by directly inhibiting signal transducer and activator of transcription 5 (STAT5) activation, which causes GH resistance under prolonged fasting, starvation, and malnutrition [6]