NNMT inhibition increases NAD+ availability, which is known to support mitochondrial function, reduce fibrosis, and lower inflammation
Similarly, women who are breastfeeding should avoid NAD+ injections, since it is unknown whether the exogenous NAD+ could affect the nursing infant or alter milk composition
The body needs enough intrinsic factor to absorb and reabsorb vitamin B 12 from the bile, the lack of which reduces the time needed to develop a deficiency
This is a compound that shifts systemic methylation balance and NAD+ economy, and nobody has published what that looks like in humans over months or years
Owing to its unique structure and mode of action, SS-31 demonstrates potential therapeutic value across cardiovascular diseases, neurodegenerative disorders, kidney injury, and myopathies associated with mitochondrial dysfunction 1-6
Why Do Some Cats Have a Vitamin B12 Deficiency