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doi: 10.1016/j.jep.2019.112209 106 TanSChenLJinLFuX

Elbini Dhouib I, Jallouli M, Annabi A, Gharbi N, Elfazaa S, Lasram MM

Age-related changes in redox status of rat serum

E.CassisL

NAC increases intracellular levels of glutathione (GSH), a key antioxidant that helps maintain cellular redox balance

At the expression level, another study found that CRISPRa was successful in upregulating the expression of TTR within dCas9-SAM transgenic mice 19 days after treatment, but this effect diminished over the course of 8 months [81]