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Our findings reveal a decreased PPAR expression in dual-culture conditions (without macrophages) and a significant upregulation in triple-culture conditions (with macrophages) upon cigarette smoke exposure (Supplementary Fig

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There were also fewer youth-rated shows with tobacco depictions: only four of the top 15 shows with tobacco depictions in 2021 were rated TV-14 and below (The Simpsons, Rick and Morty, Riverdale, and On My Block), down from seven in 2020.It is important to note, however, that youth-rated cartoons with tobacco imagery like The Simpsons and Rick and Morty are especially egregious given their format and because their plotlines have no need for historical accuracy

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Give cardiopulmonary resuscitation ( CPR)