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'It's different from many other addictive drugs, for which most people say they enjoy the first experience and would try it again.' He added: 'Our results suggest there are definitely some people who are nicotine avoiders and others who are nicotine choosers, and there are probably genetic or metabolic vulnerabilities that make people fall into one group or the other.' As part of the study, Professor Griffiths and his team 18 people who had never smoked before and gave them either a pill containing a low dose of nicotine or a placebo pill, labelled A and B
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However, over time the brain becomes desensitized to these nicotine effects, requiring you to take higher doses to achieve the same effect