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First, we conducted a similar experiment on sensor cells cultured in DMEM without pyruvate and treated with rotenone, an electron transport chain (ETC) complex I inhibitor that blocks NAD + regeneration from NADH, thereby slowing NAD + -dependent reactions in the tricarboxylic acid (TCA) cycle and impairing aspartate synthesis 2,3,4,9 (Fig

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Manufacture or production means a process, including, but not limited to, an assembly, by which merchandise is either made into a new and different article having a distinctive name, character or use

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