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This, in turn, leads to maladaptive inflammatory responses, further impairment of lung defenses and further dysbiosis of the lung microbiome, setting up the vicious circle with its attendant consequences [80]

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With respect to safety, NPs were generally very well tolerated with no serious AEs noted after administration, while six participants reported minor AEs (dizziness, headache, hot flush, hyperhidrosis and back pain) that resolved quickly

From a regulatory perspective, the practice sits in a gray area created by tax differentials

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