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PHA: PHA (polyhydroxy acid) is similar to alpha hydroxy acids (AHAs) such as glycolic acid and lactic acid, but is considered to be gentler on the skin

As per this research, the primary treatment method is supplementation with vitamin B12

JUrol 2006]

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A total of 12 events were reported in five participants (35.7%) in the normal hepatic function group, three events in three participants (42.9%) in the mild hepatic impairment group and one event in one participant (14.3%) in the moderate hepatic impairment group