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They assist in reestablishing immune homeostasis in the reproductive tract by promoting a shift in macrophage and T-cell phenotypes toward regulatory, which supports tolerance during implantation and avoids immune-mediated gamete injury

Sasatomi, and M

2014 May;34(5):427-39

As of September 2023 it is on the FDA's Category 2 list of bulk drug substances that may not be compounded due to significant safety risks, and the agency has scheduled a Pharmacy Compounding Advisory Committee (PCAC) review for July 2026 covering proposed uses in opioid withdrawal, chronic insomnia, and narcolepsy

N-Acetyl Cysteine (NAC) NAC is not glutathione itself but a precursor

doi: 10.1055/s-2007-978808