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These substances include carbon tetrachloride, chloroform, and carbon monoxide

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Endogenous interleukin-4 regulates glutathione synthesis following acetaminophen-induced liver injury in mice

Int J Environ Res Public Health 20(2):1267

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Other proposed mechanisms include direct interaction with cell surface integrins (particularly alpha-2-beta-1), effects on iron metabolism through copper-iron regulatory interactions, and epigenetic modifications