BBB disruption in the TL may be linked to anosmia because it contains important regions that form part of the primary olfactory cortex, including the piriform cortex, amygdala and entorhinal cortex, with direct connections to and from the olfactory bulb 33,34,35
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Retinol works through the retinoid receptor pathway (RAR/RXR), directly upregulating specific procollagen genes and inhibiting matrix metalloproteinases (MMPs) that break down existing collagen [6]
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Deficiency, which is common and often undiagnosed, presents as fatigue, cognitive fog, mood disruption, and immune vulnerability
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the international society for extracellular vesicles and update of the MISEV2014 guidelines