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The mortality rate for ALF varies considerably, ranging from 60 to 90%, depending on factors like the underlying cause of liver failure and the expertise of the transplant center in managing liver transplants

Continuous ROS production results in oncogene and tumor suppressor gene changes, as well as chromosomal abnormalities by oxidative genome damage, which includes the oxidation of guanine to form 8-OhdG and 8-oxo,7,8-dihydroguanosine (8-OHG) in RNA and DNA (100)

(as a percentage) of three biological replicates

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