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Cholelithiasis was not reported in placebo-treated patients

NICE guidelines on obesity management do not include B12 supplementation as a therapeutic option for weight reduction without confirmed deficiency

Many people can fulfill their B12 needs through diet alone

preclinical, not a treatment for any condition

Methionine, Inositol, and Choline help break down fats and aid in their removal from the liver, potentially promoting a more efficient metabolism

Eligible studies included randomised controlled trials, cohort, and case-control studies assessing B12 supplementation efficacy via oral, sublingual, or IM administration routes