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3 Results In this study, we aimed to determine if three drugs from the SSRI family (sertraline, fluoxetine, and citalopram), commonly used as antidepressants (Figure 1, right panel), can be repurposed as inhibitors of MRP1 and MRP7 transporters (Figure 1, left panel) to overcome MDR in cancer cells

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1 Introduction Kidney disease poses a substantial public health concern, as approximately 10% of the worldwide population is afflicted by chronic kidney disease (CKD) (Rosner et al., 2021)

and MOP-79411 and MOP-136903 to A.R., NSERC grants 109166 to N.D

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