[1] [3] Patients should be monitored for pancreatitis, gallbladder disease (right upper quadrant pain, fever, jaundice), and diabetic retinopathy complications
Eur Heart J 37(23):18501858 Heymans S, Lakdawala NK, Tschpe C, Klingel K (2023) Dilated cardiomyopathy: causes, mechanisms, and current and future treatment approaches
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3-Hydroxy-3-methylglutaryl-CoA lyase deficiency is a disorder biochemically characterized by the predominant accumulation of 3-hydroxy-3-methylglutarate (HMG), 3-methylglutarate (MGA), 3-methylglutaconate and 3-hydroxyisovalerate in tissues and in vivo administration of HMG and MGA significantly decrease GSH concentration in liver in young rats [25]