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Mitochondrial dysfunction and oxidative stress in metabolic disorders -- A step towards mitochondria based therapeutic strategies

Tudor M, Jandric I, Marovic A, Gjurasin M, Perovic D, Radic B, Blagaic AB, Kolenc D, Brcic L, Zarkovic K, Seiwerth S, Sikiric P

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In these conditions, AR that is not bound to a ligand is retained in the cytoplasm, but upon binding with dihydrotestosterone (DHT), a potent androgenic hormone, it translocates into the nucleus and promotes the transcription of targeted genes[38]

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