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The amelioration of N-acetyl-p-benzoquinone imine toxicity by ginsenoside Rg3: The role of nrf2-mediated detoxification and mrp1/mrp3 transports

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PMC 5716395

In patients taking opioids for an extended period of time at high doses, ensure that a multimodal approach to pain management, including mental health support (if needed), is in place prior to initiating an opioid analgesic taper [see DOSAGE AND ADMINISTRATION, WARNINGS]

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