BDNF, a neurotrophin involved in neuronal plasticity (Leal et al
While SSRIs are efficacious, their safety profile in terms of reproductive system toxicity remains controversial, especially in developing adolescents, fertile adults, and perinatal pregnant women ( 2 Effects of SSRIs on reproductive cytogenesis 2.1 Effects of SSRIs on male germ cells Several studies have found that fluoxetine disrupts the hypothalamuslobetestis axis, significantly decreasing the serum concentrations of luteinizing hormone (LH), follicle stimulating hormone (FSH), progesterone, and testosterone, while also affecting several sperm quality parameters, as evidenced by decreased sperm concentrations and viability, increased deoxyribonucleic acid (DNA) fragmentation, and lower reproductive organ weights (Figure 1), which could have been attributed to diminished androgen levels
2025;65(4):gnae145
This helps reduce the temperature shock to the lyophilized powder, though it is not strictly required
Hexarelin even interacts with cardiac ghrelin receptors
10.1177/03635465231182438 192 PaikJ.DugganS