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(2012), is characterized by iron-dependent accumulation of lipid peroxides, distinguishing it from classical cell death modalities such as apoptosis, necrosis, and autophagy, ferroptosis exhibits a stronger dependence on intracellular iron than other regulated cell death pathways
doi: 10.1196/annals.1428.069 97
While it is primarily known for its tissue repair capabilities , its relevance to autoimmune disease extends into two specific areas: remyelination in multiple sclerosis and general tissue repair in autoimmune-damaged organs
doi: 10.3389/fnut.2022.1043783 292 RanganPChoiIWeiMNavarreteGGuenEBrandhorstSet al
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