Data from the 2021 Nature Aging paper are particularly illuminating on this point
The following materials: Xpd TTD/TTD mice
Key Takeaways Most cases of "copper peptides ruined my skin" are actually the "copper uglies," a temporary inflammatory reaction that resolves within 2 to 6 weeks when use is adjusted correctly
TB-500 contributes unique cytoskeletal regulatory mechanisms that enable the enhanced cellular responses to GHK-Cu and BPC-157 signaling
Proposed Treatment Current KP treatments on the market all use similar keratolytics: Urea, Alpha Hydroxy Acids (AHA), or Beta Hydroxy Acids (BHA) to help chemically exfoliate the infundibular plug, reducing the bumpy texture
C57BL/6 male mice, 28 months of age, treated with GHK at a dose of 10 mg/kg body weight 5 times per week for 3 weeks showed improved learning compared to saline treated control mice